A CASE REPORT OF 41-YEAR-OLD MALE WITH POST TRAUMATIC ENCEPHALOMALACIA

Authors

  • Fathia Kharitano Universitas Pembangunan Nasional "Veteran" Jakarta Author
  • Feda Anisah Makkiyah Universitas Pembangunan Nasional "Veteran" Jakarta Author

DOI:

https://doi.org/10.00000/azy3vr10

Keywords:

Encephalomalacia, Brain injuries, Craniocerebral trauma, Headache , Patient

Abstract

Encephalomalacia is the softening of brain tissue resulting from hemorrhagic contusions, infarctions, or diffuse axonal injury, which can develop months or even years after head trauma. Encephalomalacia may occur in adults, albeit rarely, following acquired brain injuries such as infection, trauma, or infarction. We report a 41-year-old male who presented with headache and memory loss, symptoms that developed one year after a motorcycle accident in which he sustained a head injury. Imaging revealed hypodense lesions in the left temporoparietal lobe, consistent with encephalomalacia and associated ventriculomegaly. This case highlights the significance of detailed clinical and radiological assessments in diagnosing encephalomalacia, underscoring the importance of early intervention and management to prevent long-term neurological complications.

References

Abuhasan, Q., Reddy, V. and Siddiqui, W. (2025) Neuroanatomy, amygdala. Treasure Island (FL): StatPearls Publishing..

Azouvi, P., Vallat-Azouvi, C. and Belmon, A. (2009) ‘Cognitive deficits after traumatic coma’, Progress in Brain Research, 177, pp. 89–110. doi:10.1016/S0079-6123(09)17708-7.

Carmody, R.F. (2013) ‘Vascular injury and parenchymal changes’, in Imaging of the Brain. Philadelphia: Elsevier, pp. 603–625. doi:10.1016/B978-1-4160-5009-4.50034-0.

Chang, C.H., Lian, H.W. and Sung, Y.F. (2022) ‘Cystic encephalomalacia in a young woman after cardiac arrest due to diabetic ketoacidosis and thyroid storm’, Cureus, 14(3), p. e23707. doi:10.7759/cureus.23707.

Dogrul, B.N., Kiliccalan, I., Asci, E.S. and Peker, S.C. (2020) ‘Blunt trauma related chest wall and pulmonary injuries: an overview’, Chinese Journal of Traumatology, 23(3), pp. 125– 138. doi:10.1016/j.cjtee.2020.04.003.

Duff, M.C., Covington, N.V., Hilverman, C. and Cohen, N.J. (2020) ‘Semantic memory and hippocampus: revisiting, reaffirming, and extending the reach of their critical relationship’, Frontiers in Human Neuroscience, 13, p. 2019. doi:10.3389/fnhum.2019.00471.

Fan, L., Feng, L., Gan, J., Luo, R., Qu, H. and Chen, X. (2024) ‘Clinical characteristics of cystic encephalomalacia in children’, Frontiers in Pediatrics, 12, p. 1280489. doi:10.3389/fped.2024.1280489.

Ghandi, S., Sasun, A.R. and Patil, D.S. (2024) ‘Functional recovery in a patient of abnormal left parieto-occipital encephalomalacia with gliosis-associated genu varum deformity: a case report’, Cureus, 16(2), p. e55115. doi:10.7759/cureus.55115.

Harjpal, P. and Quershi, I. (2023) ‘Encephalomalacia in young adult: a rare presentation’, Medical and Pharmaceutical Sciences, 1, p. 2023090612. doi:10.20944/preprints202309.0612.v1.

Jasielski, P., Piedel, F., Piwek, M., Rocka, A., Petit, V. and Rejdak, K. (2020) ‘Application of citicoline in neurological disorders: a systematic review’, Nutrients, 12(10), p. 3113. doi:10.3390/nu12103113.

Lawrence, J.M., Schardien, K., Wigdahl, B. and Nonnemacher, M.R. (2023) ‘Roles of neuropathology-associated reactive astrocytes: a systematic review’, Acta Neuropathologica Communications, 11, p. 42. doi:10.1186/s40478-023-01526-9.

Patel, A., Biso, G.M.N.R. and Fowler, J.B. (2025) Neuroanatomy, temporal lobe. Treasure Island (FL): StatPearls Publishing.

Pekdemir, B., Raposo, A., Saraiva, A., Lima, M.J., Alsharari, Z.D., BinMowyna, M.N. and Karav,

S. (2024) ‘Mechanisms and potential benefits of neuroprotective agents in neurological health’, Nutrients, 16(24), p. 4368. doi:10.3390/nu16244368.

Puri, S., Shaheen, M. and Grover, B. (2023) ‘Nutrition and cognitive health: a life course approach’, Frontiers in Public Health, 11, p. 1023907. doi:10.3389/fpubh.2023.1023907.

Sahid, J., Kashif, A. and Shahid, M.K. (2023) ‘A comprehensive review of physical therapy interventions for stroke rehabilitation: impairment-based approaches and functional goals’, Brain Sciences, 13(5), p. 717. doi:10.3390/brainsci13050717.

Sahuquillo, J. and Dennis, J.A. (2019) ‘Decompressive craniectomy for the treatment of high intracranial pressure in closed traumatic brain injury’, Cochrane Database of Systematic Reviews, 2019(12), p. CD003983. doi:10.1002/14651858.CD003983.pub3.

Sandi, C. (2007) ‘Memory impairments associated with stress and aging’, in Bermudez-Rattoni, F. (ed.) Neural Plasticity and Memory: From Genes to Brain Imaging. Boca Raton (FL): CRC Press/Taylor & Francis.

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Published

2026-04-25

How to Cite

A CASE REPORT OF 41-YEAR-OLD MALE WITH POST TRAUMATIC ENCEPHALOMALACIA. (2026). The Health Researcher’s Journal, 3(2), 1-6. https://doi.org/10.00000/azy3vr10