A Novel Dressing for Wound Care Based on Konjac Glucomannan
Keywords:
Nutrigenomik, Nursing, Health Sciences, Public Health , Mental health, wound care , konjac glucomannanAbstract
Wound management has become a crucial component of healthcare systems since wound healing continues to be a problem for the nursing sciences. One area that could provide novel methods for regenerative complementary nursing is konjac glucomannan. It is necessary to emphasize the significance when konjac glucomannan is incorporated into biomaterials, it may induce particular qualities that make the biomaterials more effective. They are appealing as wound dressing materials. In this review, we will talk about the first line of bioactive konjac glucomannan-based dressings that are often used in nursing practice. These include semipermeable films, hydrogel dressings, hydrocolloid dressings, alginate dressings, non-adherent contact layer dressings, and multilayer dressings. This review will also point out that there isn'tenough high-quality evidence and that more advanced trials need to be done because most current wound healing treatments don't work well, either structurally or functionally. Konjac glucomannan is a unique tool that can be used to help heal wounds. They can be made to closely resemble the natural processes that lead to tissue repair.
References
Aruan, N. M., Sriyanti, I., Edikresnha, D., Suciati, T., Munir, M. M., & Khairurrijal. (2017).
Polyvinyl Alcohol/Soursop Leaves Extract Composite Nanofibers Synthesized Using
Electrospinning Technique and their Potential as Antibacterial Wound Dressing. Procedia
Engineering, 170, 31–35. https://doi.org/https://doi.org/10.1016/j.proeng.2017.03.006
Bechstein, W. O. (2018). Towards Simpler and Reliable Wound Care. In Deutsches Arzteblatt
international (Vol. 115, Issue 13, pp. 211–212). https://doi.org/10.3238/arztebl.2018.0211
Boyko, T. V, Longaker, M. T., & Yang, G. P. (2018). Review of the Current Management of
Pressure Ulcers. Advances in Wound Care, 7(2), 57–67.
https://doi.org/10.1089/wound.2016.0697
Castaño, O., Pérez-Amodio, S., Navarro-Requena, C., Mateos-Timoneda, M. Á., & Engel, E.
(2018). Instructive microenvironments in skin wound healing: Biomaterials as signal
releasing platforms. Advanced Drug Delivery Reviews, 129, 95–117.
https://doi.org/10.1016/j.addr.2018.03.012
Chamorro, A. M., Vidal Thomas, M. C., Mieras, A. S., Leiva, A., Martínez, M. P., & Hernández
Yeste, M. M. S. (2019). Multicenter randomized controlled trial comparing the
effectiveness and safety of hydrocellular and hydrocolloid dressings for treatment of
category II pressure ulcers in patients at primary and long-term care institutions.
International Journal of Nursing Studies, 94, 179–185.
https://doi.org/10.1016/j.ijnurstu.2019.03.021
Chou, H.-Y., Weng, C.-C., Lai, J.-Y., Lin, S.-Y., & Tsai, H.-C. (2020). Design of an
Interpenetrating Polymeric Network Hydrogel Made of Calcium-Alginate from a Thermos-Sensitive Pluronic Template as a Thermal-Ionic Reversible Wound Dressing. Polymers,
(9). https://doi.org/10.3390/polym12092138
Clark, M. (2018). Alginates in Dressings and Wound Management. In B. H. A. Rehm & M. F.
Moradali (Eds.), Alginates and Their Biomedical Applications (pp. 213–222). Springer
Singapore. https://doi.org/10.1007/978-981-10-6910-9_8
Cuschieri, L., Debosz, J., Miiller, P., & Celis, M. (2013). Autolytic debridement of a large,
necrotic, fully occluded foot ulcer using a hydrocolloid dressing in a diabetic patient.
Advances in Skin and Wound Care, 26(7), 300–304.
https://doi.org/10.1097/01.ASW.0000429779.48138.c0
Derwin R, M. Z. E. H., & Webster, J. (2018). Hydrocolloid dressings for donor sites of split
thickness skin grafts. Cochrane Database of Systematic Reviews, 1.
https://doi.org/10.1002/14651858.CD012634.pub2
Enescu, D. M., Stoicescu, S., Tomiţă, M., Nacea, I., Ioniţă, D., & Tatar, R. (2020). Management
of lower extremity traumatic injuries with negative pressure wound therapy: Experience of
a pediatric plastic surgery department. Injury, 51 Suppl 4, S9–S15.
https://doi.org/10.1016/j.injury.2020.03.027
Halim, A. S., Nor, F. M., Mat Saad, A. Z., Mohd Nasir, N. A., Norsa’adah, B., & Ujang, Z.
(2018). Efficacy of chitosan derivative films versus hydrocolloid dressing on superficial
wounds. Journal of Taibah University Medical Sciences, 13(6), 512–520.
https://doi.org/10.1016/j.jtumed.2018.10.004
İnal, M., & Mülazımoğlu, G. (2019). Production and characterization of bactericidal wound
dressing material based on gelatin nanofiber. International Journal of Biological
Macromolecules, 137, 392–404. https://doi.org/10.1016/j.ijbiomac.2019.06.119
Janowska, A., Macchia, M., & Paggi, B. (2018). Advanced Dressings in Pressure Ulcers. In M.
Romanelli, M. Clark, A. Gefen, & G. Ciprandi (Eds.), Science and Practice of Pressure
Ulcer Management (pp. 159–173). Springer London. https://doi.org/10.1007/978-1-4471-
-4_12
Kong, D., Zhang, Q., You, J., Cheng, Y., Hong, C., Chen, Z., Jiang, T., & Hao, T. (2020).
Adhesion loss mechanism based on carboxymethyl cellulose-filled hydrocolloid dressings
in physiological wounds environment. Carbohydrate Polymers, 235, 115953.
https://doi.org/10.1016/j.carbpol.2020.115953
Li, X., Xu, G., & Chen, J. (2015). Tissue engineered skin for diabetic foot ulcers: A meta-
analysis. International Journal of Clinical and Experimental Medicine, 8(10), 18191–
Ma, R., Wang, Y., Qi, H., Shi, C., Wei, G., Xiao, L., Huang, Z., Liu, S., Yu, H., Teng, C., Liu,
H., Murugadoss, V., Zhang, J., Wang, Y., & Guo, Z. (2019). Nanocomposite sponges of
sodium alginate/graphene oxide/polyvinyl alcohol as potential wound dressing: In vitro and
in vivo evaluation. Composites Part B: Engineering, 167, 396–405.
https://doi.org/https://doi.org/10.1016/j.compositesb.2019.03.006
Matsuzaki, K., Yokono, C., Nomura, Y., & Toriumi, M. (2018). Wound dressings for diabeticfoot ulcers. Japanese Journal of Plastic Surgery, 61(8), 958–970.
https://doi.org/10.1007/978-3-319-89869-8
Mir, M., Ali, M. N., Barakullah, A., Gulzar, A., Arshad, M., Fatima, S., & Asad, M. (2018).
Synthetic polymeric biomaterials for wound healing: a review. Progress in Biomaterials,
(1), 1–21. https://doi.org/10.1007/s40204-018-0083-4
Moore, Z. E. H., & Webster, J. (2018). Dressings and topical agents for preventing pressure
ulcers. Cochrane Database of Systematic Reviews, 2018(12).
https://doi.org/10.1002/14651858.CD009362.pub3
Nunes, P. S., Albuquerque, R. L. C. J., Cavalcante, D. R. R., Dantas, M. D. M., Cardoso, J. C.,
Bezerra, M. S., Souza, J. C. C., Serafini, M. R., Quitans, L. J. J., Bonjardim, L. R., &
Araújo, A. A. S. (2011). Collagen-based films containing liposome-loaded usnic acid as
dressing for dermal burn healing. Journal of Biomedicine & Biotechnology, 2011, 761593.
https://doi.org/10.1155/2011/761593
Qu, J., Zhao, X., Liang, Y., Xu, Y., Ma, P. X., & Guo, B. (2019). Degradable conductive
injectable hydrogels as novel antibacterial. Chemical Engineering Journal, 362, 548–560.
https://doi.org/https://doi.org/10.1016/j.cej.2019.01.028
Stoica, A. E., Chircov, C., & Grumezescu, A. M. (2020). Nanomaterials for Wound Dressings:
An Up-to-Date Overview. Molecules, 25, 2699.
sugeng mashudi, Dhianita, Aziz, & Syafira. (2022). Effects of Konjac Glucomannan on Blood
Profile in Schizophrenia with Hyperglycemia: Pra Eksperimental Study. International
Journal of Public Health, 1(6).
Tamahkar, E., Özkahraman, B., Süloğlu, A. K., İdil, N., & Perçin, I. (2020). A novel multilayer
hydrogel wound dressing for antibiotic release. Journal of Drug Delivery Science and
Technology, 58, 101536. https://doi.org/https://doi.org/10.1016/j.jddst.2020.101536
Tao, G., Wang, Y., Cai, R., Chang, H., Song, K., Zuo, H., Zhao, P., Xia, Q., & He, H. (2019).
Design and performance of sericin/poly(vinyl alcohol) hydrogel as a drug delivery carrier
for potential wound dressing application. Materials Science & Engineering. C, Materials
for Biological Applications, 101, 341–351. https://doi.org/10.1016/j.msec.2019.03.111
Tsioli, V., Gouletsou, P. G., Galatos, A. D., Psalla, D., Lymperis, A., Sideri, A. I., & Papazoglou,
L. G. (2018). The Effect of a Hydrocolloid Dressing on Second Intention Wound Healing in
Cats. Journal of the American Animal Hospital Association, 54(3), 125–131.
https://doi.org/10.5326/JAAHA-MS-6604
Wang, H., Xu, Z., Zhao, M., Liu, G., & Wu, J. (2021). Advances of hydrogel dressings in
diabetic wounds. Biomater. Sci., 9(5), 1530–1546. https://doi.org/10.1039/D0BM01747G
